Felicity N.E. Gavins
Director of the Small Animal Research Facilty at LSU Health - Shreveport
Ph.D., 2004, Queen Mary University
Department of Molecular and Cellular Physiology
LSU Health Sciences Center
1501 Kings Highway
Shreveport, LA 71130
Inflammation and microvascular dysfunction have been implicated in a variety of pathologic conditions affecting the body, such as myocardial infarction and stroke. Features of the inflammatory response common to many of these pathological conditions are manifested in the microvasculature (including: oxidative stress, diminished endothelial barrier function, increased expression of endothelial cell adhesion molecules, and the recruitment of rolling and adherent leukocytes and platelets).
My research crosses the boundaries between Integrative Physiology and Pharmacology and uses multidisciplinary approaches to advance understanding of the vascular physiology and pathophysiology of inflammatory and related disorders, at the molecular, cellular, tissue and whole organism levels. In particular I focus on the microcirculation, studying leukocyte trafficking and endothelial dysfunction in both the brain and the periphery, using a variety of imaging techniques, including: confocal intravital microscopy; magnetic resonance imaging (MRI); positron emission tomography (PET) and single photon emission tomography (SPECT). My research incorporates translational pharmacology and therapeutic innovation, including stem cell therapy.
Clinical specialty relevant to: Cardiology, Neurology, and vascular surgery.
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